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Peptide record

TPDB63798

mPCI Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB63798
mPCI
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 18-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RRHSHSKKKKAKESSVGA
Physicochemical Analysis
C84H149N33O25
NDCQILMFPTWY
K
2021.31
11.68
9
1
3
+6
10.77
-1.900
27.22
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
4
Residue Composition
number
2
A
2
R
0
N
0
D
0
C
1
E
0
Q
1
G
2
H
0
I
0
L
5
K
0
M
0
F
0
P
4
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 2 I: 0 L: 0 K: 5 M: 0 F: 0 P: 0 S: 4 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
18
C84H149N33O25
2021.31
11.68
+6
10.77
-1.900
Free
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Jurkat T Cells And U937 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
FITC-labelled
Cytoplasm and nucleus
In vitro
CCCSCCCCSSCCSSCC
Additional Detail Fields 1 fields
CCCSCCCCSSCCSSCC