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Peptide record

TPDB63775

pAntpHD (3Pro) Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB63775
pAntpHD (3Pro)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Biotinylation
Sequence
RQPKIWFPNRRKPWKK-NH2
Physicochemical Analysis
C103H161N33O19
ADCEGHLMSTYV
K
2165.62
12.72
7
0
4
+7
3.60
-2.212
24.38
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
507.94
2
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
0
L
4
K
0
M
1
F
3
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 0 K: 4 M: 0 F: 1 P: 3 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
16
C103H161N33O19
2165.62
12.72
+7
3.60
-2.212
Amidation
L
Linear
Biotinylation
N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Cortical striatal cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Biotin
Cytoplasm
Similar to (pAntp) (43-58)
Non-receptor mediated endocytosis
In vitro
CCCCCCCTTCCSSSCC
Additional Detail Fields 1 fields
CCCCCCCTTCCSSSCC