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Peptide record

TPDB63765

Penetratin-VTPVCTA Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB63765
Penetratin-VTPVCTA
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 23-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: 5-fluorescein thioureide (Flut) labeled
Sequence
RQIKIWFQNRRMKWKKVTPVCTA
Physicochemical Analysis
C133H217N41O29S2
DEGHLSY
K
2918.56
12.16
7
0
9
+7
2.75
-0.783
63.48
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
376.90
6
Residue Composition
number
1
A
3
R
1
N
0
D
1
C
0
E
2
Q
0
G
0
H
2
I
0
L
4
K
1
M
1
F
1
P
0
S
2
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 3 N: 1 D: 0 C: 1 E: 0 Q: 2 G: 0 H: 0 I: 2 L: 0 K: 4 M: 1 F: 1 P: 1 S: 0 T: 2 W: 2 Y: 0 V: 2
Chemical Descriptors
23
C133H217N41O29S2
2918.56
12.16
+7
2.75
-0.783
Free
5-fluorescein thioureide (Flut) labeled
L
Linear
Free
N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
S-linked UDP peptide
Endosomes
In vitro
CCSSTTTTSCCC
Additional Detail Fields 1 fields
CCSSTTTTSCCC