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Peptide record

TPDB63748

Cell-penetrating Peptides standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB63748
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 28-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RQIKIWFQNRRMKWKKGGTALDSWLQTE
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C159H250N48O40S1
CHPYV
K
3506.09
11.53
7
2
10
+5
2.81
-1.168
59.29
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
16500
4.71
7
Residue Composition
number
1
A
3
R
1
N
1
D
0
C
1
E
3
Q
2
G
0
H
2
I
2
L
4
K
1
M
1
F
0
P
1
S
2
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 1 D: 1 C: 0 E: 1 Q: 3 G: 2 H: 0 I: 2 L: 2 K: 4 M: 1 F: 1 P: 0 S: 1 T: 2 W: 3 Y: 0 V: 0
Chemical Descriptors
28 reviewed residue count
C159H250N48O40S1 sequence-only estimate (linear, free termini)
3506.09 sequence-only estimate (linear, free termini)
11.53 sequence-only estimate (linear, free termini)
+5 sequence-only estimate (linear, free termini)
2.81 sequence-only estimate (linear, free termini)
-1.168 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.