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Peptide record

TPDB63746

CPP-hnRNPK-RGG (Penetratin) Cell-penetrating Peptides standard
54 amino acids
Basic Information
3D PDB MODEL
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TPDB63746
CPP-hnRNPK-RGG (Penetratin)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 54-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RQIKIWFQNRRMKWKKGGMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGHHHHHH
Physicochemical Analysis
C286H439N105O64S5
ACELSTY
RG
6532.60
12.58
20
3
14
+12
15.07
-1.465
19.81
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
168.39
3
Residue Composition
number
0
A
10
R
1
N
3
D
0
C
0
E
2
Q
10
G
6
H
2
I
0
L
4
K
5
M
4
F
4
P
0
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 10 N: 1 D: 3 C: 0 E: 0 Q: 2 G: 10 H: 6 I: 2 L: 0 K: 4 M: 5 F: 4 P: 4 S: 0 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
54
C286H439N105O64S5
6532.60
12.58
+12
15.07
-1.465
Free
L
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hek293 Cells , MDA-MB231, Umuc3, Hct116, Du145, Hff1, Ht1080, MCF10A

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Chimeric
hnRNPK RGG-domain
Cytoplasm and nucleus
In vitro