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Peptide record

TPDB63744

CPP Cell-penetrating Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB63744
CPP
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 24-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RQIKIWFQNRRMKWKKGGHHHHHH
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C144H216N54O28S1
ADCELPSTYV
H
3183.70
12.72
13
0
6
+8
3.79
-1.988
32.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
3.46
3
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
0
E
2
Q
2
G
6
H
2
I
0
L
4
K
1
M
1
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 2 G: 2 H: 6 I: 2 L: 0 K: 4 M: 1 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
24 reviewed residue count
C144H216N54O28S1 sequence-only estimate (linear, free termini)
3183.70 sequence-only estimate (linear, free termini)
12.72 sequence-only estimate (linear, free termini)
+8 sequence-only estimate (linear, free termini)
3.79 sequence-only estimate (linear, free termini)
-1.988 sequence-only estimate (linear, free termini)
Free Activity
L Activity
Linear Activity
Free Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Bc Cell Lines

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Chimeric
Nucleus
In vitro