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Peptide record

TPDB63713

Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB63713
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 18-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RQIKIWFQCRMKWKKNRC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C110H178N36O22S3
ADEGHLPSTYV
K
2453.03
11.53
7
0
6
+7
3.46
-1.261
43.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11125
4.54
5
Residue Composition
number
0
A
3
R
1
N
0
D
2
C
0
E
2
Q
0
G
0
H
2
I
0
L
4
K
1
M
1
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 2 E: 0 Q: 2 G: 0 H: 0 I: 2 L: 0 K: 4 M: 1 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
18 reviewed residue count
C110H178N36O22S3 sequence-only estimate (linear, free termini)
2453.03 sequence-only estimate (linear, free termini)
11.53 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
3.46 sequence-only estimate (linear, free termini)
-1.261 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.