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Peptide record

TPDB63708

Antp Cell-penetrating Peptides modified_plain modified

16 amino acids

3D PDB MODEL

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Standard-residue backbone model; source-recorded chemical modifications are not verified in these coordinates.

TPDB ID TPDB63708

Peptide_Name

Antp

Activity

Cell-penetrating Peptides

Activity_category_statistics

Delivery and barrier-penetrating peptides

Database_Source

CPPsite3.0

Sequence_Type

modified_plain

Has_Modification Yes

Description A 16-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.

Modification

N-terminal: FITC-labelled

Sequence

RQIKIWEQNRRMKWKK

FASTA

>TPDB63708|Cell-penetrating Peptides|length=16
RQIKIWEQNRRMKWKK

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Length

16 reviewed residue count

C_terminal_Modification

Free Activity

Chirality

L Activity

Linearity

Linear Activity

N_terminal_Modification

FITC-labelled Activity

SMILES

N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)O Activity

Evidence 1 Activity

Activity

Detail Source Activity Cell-penetrating Peptides

Target

Cell Line A549 Cells

Assay & Model

In Vitro Model Female athymic nude mice (6–8 weeks of age)

In Vivo Model Female athymic nude mice (6–8 weeks of age)

Source & Reference

Database Source CPPsite3.0

Source CPPsite3

Other

Source Activity Label	Source Definition
Cell-penetrating Peptides	CPPsite3.0 experimentally validated cell-penetrating peptide annotation.

CPP Category Natural residues Linear L

Source of Peptide Protein derived

Cargo Type IH13 derived from BIRC5 (1H13-BIRC5)

Subcellular Localization Cytoplasm

In Vitro or In Vivo In vitro and in vivo

DSSP Secondary Structure CTTTC

DSSP_Secondary_Structure

CTTTC