Peptide record

TPDB63708

Antp Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB63708
Antp
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: FITC-labelled
Sequence
RQIKIWEQNRRMKWKK
Physicochemical Analysis
C100H166N34O22S1
ADCGHLFPSTYV
K
2228.69
12.16
7
1
5
+6
5.44
-2.125
48.75
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
493.56
3
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
1
E
2
Q
0
G
0
H
2
I
0
L
4
K
1
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 1 Q: 2 G: 0 H: 0 I: 2 L: 0 K: 4 M: 1 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
16
C100H166N34O22S1
2228.69
12.16
+6
5.44
-2.125
Free
L
Linear
FITC-labelled
N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

A549 Cells

Assay & Model

Female athymic nude mice (6–8 weeks of age)
Female athymic nude mice (6–8 weeks of age)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
IH13 derived from BIRC5 (1H13-BIRC5)
Cytoplasm
In vitro and in vivo
CTTTC
Additional Detail Fields 1 fields
CTTTC