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Peptide record

TPDB63707

Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB63707
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 23-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RQIKIWCFPHEQNRRLKFTRPKK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C137H221N45O30S1
ADGMSYV
RK
3010.61
11.99
9
1
6
+7
3.88
-1.509
50.87
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
1.83
5
Residue Composition
number
0
A
4
R
1
N
0
D
1
C
1
E
2
Q
0
G
1
H
2
I
1
L
4
K
0
M
2
F
2
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 1 D: 0 C: 1 E: 1 Q: 2 G: 0 H: 1 I: 2 L: 1 K: 4 M: 0 F: 2 P: 2 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
23 reviewed residue count
C137H221N45O30S1 sequence-only estimate (linear, free termini)
3010.61 sequence-only estimate (linear, free termini)
11.99 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
3.88 sequence-only estimate (linear, free termini)
-1.509 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.