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Peptide record

TPDB63699

pAntp mutant Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB63699
pAntp mutant
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with hca (4-(7-hydroxycoumaryl)-acetyl)
Sequence
RQIKIFFQNRRMKWKK-NH2
Physicochemical Analysis
C102H167N33O20S1
ADCEGHLPSTYV
K
2207.72
12.72
7
0
6
+7
3.01
-1.500
48.75
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
249.13
3
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
0
E
2
Q
0
G
0
H
2
I
0
L
4
K
1
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 2 L: 0 K: 4 M: 1 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
16
C102H167N33O20S1
2207.72
12.72
+7
3.01
-1.500
Amidation
L
Amphipathic
Linear
Conjugation with hca (4-(7-hydroxycoumaryl)-acetyl)
N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

NIH-3T3

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Protein derived
Fluorophore [hca (4-(7-hydroxycoumaryl)-acetyl)]
Cytoplasm and nucleus
In vitro
CCCCSCCSCCCTTTTC
Additional Detail Fields 1 fields
CCCCSCCSCCCTTTTC