Back to search

Peptide record

TPDB63677

pAntp (53-58) Cell-penetrating Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63677
pAntp (53-58)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 6-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Biotinylation (Labeled with Biotinyl-beta-Alanine)
Sequence
RMKWKK-NH2
Physicochemical Analysis
C40H69N13O7S1
ANDCEQGHILFPSTYV
K
876.13
11.73
4
0
2
+4
1.70
-2.533
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
627.76
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
1
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 1 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
6
C40H69N13O7S1
876.13
11.73
+4
1.70
-2.533
Amidation
L
Linear
Biotinylation (Labeled with Biotinyl-beta-Alanine)
N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HaCat/ A549 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Biotin
Probably Cytosol and nucleus, nucleoi
Low (25% relative to (pAntp) (43-58))
Non-endocytic mechanism
In vitro
CCSCCC
Additional Detail Fields 1 fields
CCSCCC