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Peptide record

TPDB63671

PN366 (SEQ ID NO: 46) Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB63671
PN366 (SEQ ID NO: 46)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
RLWRALPRVLRRLLRP-NH2
Physicochemical Analysis
C95H167N35O17
NDCEQGHIKMFSTY
R
2071.60
13.10
6
0
8
+6
1.01
-0.381
146.25
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
265.50
0
Residue Composition
number
1
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
5
L
0
K
0
M
0
F
2
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 5 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
16
C95H167N35O17
2071.60
13.10
+6
1.01
-0.381
Amidation
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CGGGTTHHHHTTTCCC
Additional Detail Fields 1 fields
CGGGTTHHHHTTTCCC