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Peptide record

TPDB63651

α-NLS-C Cell-penetrating Peptides modified_plain modified
27 amino acids
Basic Information
3D PDB MODEL
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Standard-residue backbone model; source-recorded chemical modifications are not verified in these coordinates.

TPDB63651
α-NLS-C
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 27-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: α-pheromon N-terminal: Conjugated with TAMRA
Sequence
RLWHWLQLKPGQPMYWRQPKSKRKVRR
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
27 reviewed residue count
Free Activity
α-pheromon Activity
L Activity
Linear Activity
Conjugated with TAMRA Activity
N[C@@H](Cc1ccccc1)C(=O)/N=C/C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

S. Cerevisiae (Mata And Matα ), Hek293T , Hek293T-Nep And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
TAMRA dye
MATa cells exposed to the α-NLS-C peptide presented more selectivity towards MATα cells than NLS-α-CE and chimera peptides.
In vitro
CCTTSSCCCCC
Additional Detail Fields 1 fields
CCTTSSCCCCC