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Peptide record

TPDB63634

No.14-24 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB63634
No.14-24
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Conjugation with fluorescein
Sequence
RLLMRLYSPTTRRYG
Physicochemical Analysis
C83H139N27O21S1
ANDCEQHIKFWV
R
1883.25
11.94
4
0
6
+4
0.32
-0.767
78.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
2980
158.24
5
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
3
L
0
K
1
M
0
F
1
P
1
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 3 K: 0 M: 1 F: 0 P: 1 S: 1 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
15
C83H139N27O21S1
1883.25
11.94
+4
0.32
-0.767
Free
L
Amphipathic
Linear
Conjugation with fluorescein
N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Fluorophore (fluorescein)
Very low and not detected at 25 micromolar concent
In vitro
CCCCCCCCCCSCCCC
Additional Detail Fields 1 fields
CCCCCCCCCCSCCCC