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Peptide record

TPDB63629

C4 Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB63629
C4
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 18-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, and Peptipedia, with an available 3D structural model.
Sequence
RLHLRLHLRHLRHHLRLH
Physicochemical Analysis
C108H181N45O19
ANDCEQGIKMFPSTWYV
L
2413.92
13.00
11
0
7
+6
5.89
-0.839
151.67
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
6
H
0
I
7
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 6 I: 0 L: 7 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C108H181N45O19
2413.92
13.00
+6
5.89
-0.839
Free
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

C166-eGFP cells

Source & Reference

CPPsite3.0
CPPsite3
WO 2011/020188 A1

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCCCCSSCCSCC
Additional Detail Fields 1 fields
CCCCCSSCCSCC