Back to search

Peptide record

TPDB63616

Djeya1 Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63616
Djeya1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 18-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acylation
Sequence
RKLAFRYRRIKELYNSYR-NH2
Physicochemical Analysis
C111H178N36O26
DCQGHMPTWV
R
2432.86
11.36
7
1
8
+6
3.05
-1.406
70.56
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
4470
183.73
5
Residue Composition
number
1
A
5
R
1
N
0
D
0
C
1
E
0
Q
0
G
0
H
1
I
2
L
2
K
0
M
1
F
0
P
1
S
0
T
0
W
3
Y
0
V
Amino Acid Distribution
A: 1 R: 5 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 2 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 3 V: 0
Chemical Descriptors
18
C111H178N36O26
2432.86
11.36
+6
3.05
-1.406
Amidation
L
Cationic
Linear
Acylation
N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U373MG cells

Assay & Model

Schmidtea mediterranea (planaria)
Schmidtea mediterranea (planaria)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
6-carboxytetramethylrhodamine (TAMRA) dye
Greatest translocation efficacy of 3.80 ± 0.09 higher than C105Y and Tat
In vitro and in vivo
CCCCHHHHHHHHTSTTSCTTTHHHHSSCCC
Additional Detail Fields 1 fields
CCCCHHHHHHHHTSTTSCTTTHHHHSSCCC