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Peptide record

TPDB63609

DPV3 Cell-penetrating Peptides standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB63609
DPV3
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 17-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
Sequence
RKKRRRESRKKRRRESC
Physicochemical Analysis
C91H175N45O24S1
ANDQGHILMFPTWYV
R
2315.74
12.41
12
2
0
+10
14.50
-3.394
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
3
Residue Composition
number
0
A
8
R
0
N
0
D
1
C
2
E
0
Q
0
G
0
H
0
I
0
L
4
K
0
M
0
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 1 E: 2 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C91H175N45O24S1
2315.74
12.41
+10
14.50
-3.394
L
Linear
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, PC-3, NCI-H460 and MDA-MB-231

Source & Reference

CPPsite3.0
CPPsite3
US 20090186802

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Nucleic acid (siRNA)
Cytoplasm
Endocytic pathway
In vitro
CCCCSCCHHHHHSCCCC
Additional Detail Fields 1 fields
CCCCSCCHHHHHSCCCC