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Peptide record

TPDB63605

TATMUC1Kb Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB63605
TATMUC1Kb
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 18-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RKKRRQRRRSAPDTRPAP
Physicochemical Analysis
C91H166N42O24
NCEGHILMFWYV
R
2232.59
12.80
9
1
2
+8
10.74
-2.722
11.11
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
3
Residue Composition
number
2
A
7
R
0
N
1
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
2
K
0
M
0
F
3
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 7 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 3 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C91H166N42O24
2232.59
12.80
+8
10.74
-2.722
Free
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Dc2.4 Cells

Assay & Model

C57BL/6 mice,OT-I mice
C57BL/6 mice,OT-I mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
MUC1-H-2Kb Epitope
Cytoplasm
TATMUC1Kb show substantial peptide internalisation of 90%
Macropinocytosis or Phagocytosis
In vitro and in vivo
CCCSSSTTCCCTTTTC
Additional Detail Fields 1 fields
CCCSSSTTCCCTTTTC