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Peptide record

TPDB63599

TAT-GFP11 Cell-penetrating Peptides standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB63599
TAT-GFP11
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 29-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RKKRRQRRRGSGSRDHMVLHEYVNAAGIT
Physicochemical Analysis
C142H244N58O40S1
CFPW
R
3435.92
12.29
11
2
8
+7
12.01
-1.459
53.79
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
43.37
6
Residue Composition
number
2
A
7
R
1
N
1
D
0
C
1
E
1
Q
3
G
2
H
1
I
1
L
2
K
1
M
0
F
0
P
2
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 7 N: 1 D: 1 C: 0 E: 1 Q: 1 G: 3 H: 2 I: 1 L: 1 K: 2 M: 1 F: 0 P: 0 S: 2 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
29
C142H244N58O40S1
3435.92
12.29
+7
12.01
-1.459
Free
L
Cationic
Linear
Free
N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

N. Benthamiana

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Chimeric
GFP11 peptide
Cytoplasm And Nucleolar
TAT being 0.87 times as effective as R9
In vitro
CCCCCCCCCCCSSSSSSCCCCCCCCCCCCSCC
Additional Detail Fields 1 fields
CCCCCCCCCCCSSSSSSCCCCCCCCCCCCSCC