Back to search

Peptide record

TPDB63596

R44KP (TAT + AF + Antp) Cell-penetrating Peptides standard
44 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63596
R44KP (TAT + AF + Antp)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 44-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: GGGG as a Linker
Sequence
RKKRRQRRRGGGGITDFGIFIGLGGGGSRQIKIWFQNRRMKWKK
Physicochemical Analysis
C230H381N83O53S1
ACEHPYV
G
5189.14
12.95
15
1
12
+14
7.56
-1.184
53.18
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
211.98
6
Residue Composition
number
0
A
9
R
1
N
1
D
0
C
0
E
3
Q
10
G
0
H
5
I
1
L
6
K
1
M
3
F
0
P
1
S
1
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 9 N: 1 D: 1 C: 0 E: 0 Q: 3 G: 10 H: 0 I: 5 L: 1 K: 6 M: 1 F: 3 P: 0 S: 1 T: 1 W: 2 Y: 0 V: 0
Chemical Descriptors
44
C230H381N83O53S1
5189.14
12.95
+14
7.56
-1.184
Free
GGGG as a Linker
L
Linear
Free
N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Bt474 Cells S. Aureus, Mrsa, And B. Cereus

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
Amyloidogenic fragment (AF) in between N and C Terminal
In vitro
CCCSSSCCIIIIIICTTCCCCCTTSSSSSCC
Additional Detail Fields 1 fields
CCCSSSCCIIIIIICTTCCCCCTTSSSSSCC