Back to search

Peptide record

TPDB63587

Cell-penetrating Peptides standard
66 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63587
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 66-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RKKRRQRRREIWIAQELRRIGDEFNAYYARLLCCLLRAYYANFEDGIRRLEQAIWIERRRQRRKKR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C374H614N132O93S2
HMPSTV
R
8511.94
11.75
22
8
26
+14
4.55
-1.245
80.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
17085
2.01
12
Residue Composition
number
6
A
18
R
2
N
2
D
2
C
6
E
4
Q
2
G
0
H
6
I
6
L
4
K
0
M
2
F
0
P
0
S
0
T
2
W
4
Y
0
V
Amino Acid Distribution
A: 6 R: 18 N: 2 D: 2 C: 2 E: 6 Q: 4 G: 2 H: 0 I: 6 L: 6 K: 4 M: 0 F: 2 P: 0 S: 0 T: 0 W: 2 Y: 4 V: 0
Chemical Descriptors
66 reviewed residue count
C374H614N132O93S2 sequence-only estimate (linear, free termini)
8511.94 sequence-only estimate (linear, free termini)
11.75 sequence-only estimate (linear, free termini)
+14 sequence-only estimate (linear, free termini)
4.55 sequence-only estimate (linear, free termini)
-1.245 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.