Back to search

Peptide record

TPDB63586

TatBim Cell-penetrating Peptides standard
33 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63586
TatBim
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 33-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RKKRRQRRREIWIAQELRRIGDEFNAYYARLLC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C187H308N66O47S1
HMPSTV
R
4264.98
11.60
11
4
13
+7
4.55
-1.245
80.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
8480
1.99
6
Residue Composition
number
3
A
9
R
1
N
1
D
1
C
3
E
2
Q
1
G
0
H
3
I
3
L
2
K
0
M
1
F
0
P
0
S
0
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 3 R: 9 N: 1 D: 1 C: 1 E: 3 Q: 2 G: 1 H: 0 I: 3 L: 3 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 0
Chemical Descriptors
33 reviewed residue count
C187H308N66O47S1 sequence-only estimate (linear, free termini)
4264.98 sequence-only estimate (linear, free termini)
11.60 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
4.55 sequence-only estimate (linear, free termini)
-1.245 sequence-only estimate (linear, free termini)
Free Activity
L Activity
Cationic Activity
Linear Activity
Free Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic
Chimeric
AT520-labeled
Mean fluorescence intensity of diTatBim was approximately twice as higher than that of mTatBim
In vitro