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Peptide record

TPDB63582

Tat-C-RP7 Cell-penetrating Peptides modified_plain modified
17 amino acids
Basic Information
3D PDB MODEL
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Standard-residue backbone model; source-recorded chemical modifications are not verified in these coordinates.

TPDB63582
Tat-C-RP7
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 17-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with FITC
Sequence
RKKRRQRRRCRPARPAR
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
17 reviewed residue count
Free Activity
L Activity
Linear Activity
Conjugated with FITC Activity
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)O Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HUVECs And U87-Luc-Mcherry Cells

Assay & Model

Female Balb/c-nu mice (7–8 weeks old)
Female Balb/c-nu mice (7–8 weeks old)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
NRP1 targeting peptide RP7 and FITC dye
Cytoplasm and nucleus
Tat-C-RP7 was a more potent penetrating peptide than Tat
In vitro and in vivo
CCCSCCCCCCCCCSSCC
Additional Detail Fields 1 fields
CCCSCCCCCCCCCSSCC