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Peptide record

TPDB63572

Pepfect 1 Cell-penetrating Peptides modified_plain modified
19 amino acids
Basic Information
3D PDB MODEL
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TPDB63572
Pepfect 1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 19-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: X, 4-amino-butanoic acid N-terminal: Stearylation
Sequence
RKKRKKKRXRHXRHXRHXR-NH2
Physicochemical Analysis
C90H167N47O16
ANDCEQGILMFPSTWYV
R
2163.62
13.18
15
0
0
+12
13.50
-3.189
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
7
R
0
N
0
D
0
C
0
E
0
Q
0
G
3
H
0
I
0
L
5
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 7 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 3 I: 0 L: 0 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
19
C90H167N47O16
2163.62
13.18
+12
13.50
-3.189
Amidation
X, 4-amino-butanoic acid
Modified
Linear
Stearylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa cells

Source & Reference

CPPsite3.0
CPPsite3
US 2014/0140929 A1

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified
Synthetic
Nucelic acid (pGL3 plasmid)
Endocytosis
In vitro