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Peptide record

TPDB63564

TP5-iRGD peptide Cell-penetrating Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB63564
TP5-iRGD peptide
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 14-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RKDVYCRGDKGPDC
Physicochemical Analysis
C65H106N22O22S2
ANEQHILMFSTW
D
1611.81
8.27
4
3
2
+1
6.41
-1.557
20.71
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1615
100.20
3
Residue Composition
number
0
A
2
R
0
N
3
D
2
C
0
E
0
Q
2
G
0
H
0
I
0
L
2
K
0
M
0
F
1
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 3 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
14
C65H106N22O22S2
1611.81
8.27
+1
6.41
-1.557
Free
L
Cyclic
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MCF-7, MDA-MB-231 And Hs27 Cell

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Cyclic L
Synthetic
Zerumbone (ZER) and ZER-HPβCD
In vitro
CCCSCSSSSCSSCC
Additional Detail Fields 1 fields
CCCSCSSSSCSSCC