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Peptide record

TPDB63558

LR20 Cell-penetrating Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB63558
LR20
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 20-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
C-terminal: Conjugation with nanoparticle
Sequence
RILQQLLFIHFRIGCRHSRI
Physicochemical Analysis
C114H188N38O24S1
ANDEKMPTWYV
RI
2507.05
12.40
6
0
9
+4
1.04
0.245
136.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
4
Residue Composition
number
0
A
4
R
0
N
0
D
1
C
0
E
2
Q
1
G
2
H
4
I
3
L
0
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 1 E: 0 Q: 2 G: 1 H: 2 I: 4 L: 3 K: 0 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C114H188N38O24S1
2507.05
12.40
+4
1.04
0.245
Conjugation with nanoparticle
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3
US 20100203611

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nanoparticle
Cytoplasm and nucleus
In vitro
CHHHHHHHSSCCCCSCCC
Additional Detail Fields 1 fields
CHHHHHHHSSCCCCSCCC