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Peptide record

TPDB63519

RPV Cell-penetrating Peptides modified_plain modified
9 amino acids
Basic Information
3D PDB MODEL
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Standard-residue backbone model; source-recorded chemical modifications are not verified in these coordinates.

TPDB63519
RPV
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 9-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: Liposomes
Sequence
RGDPFVYLI
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
9 reviewed residue count
Free Activity
Liposomes Activity
L Activity
Linear Activity
Free Activity
N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)O Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human Nsclc A549 Cells

Assay & Model

Tumor-bearing nude mice (Male BALB/c nude mice, weighing 20 ± 2 g)
Tumor-bearing nude mice (Male BALB/c nude mice, weighing 20 ± 2 g)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Epirubicin and Dioscin
Cellular Membrane And The Nuclei
Order of fluorescence intensity: free epirubicin >RPV-modified epirubicin and dioscin co-delivery liposomes >epirubicin and dioscin co-delivery liposomes ≥epirubicin liposomes
In vitro and in vivo
CTTCC
Additional Detail Fields 1 fields
CTTCC