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Peptide record

TPDB63518

P2 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB63518
P2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
Chemical: Linker 6-aminohexamoic acid (Ahx) N-terminal: Conjugation with FITC
Sequence
RGDGPRRRPRKRRGR
Physicochemical Analysis
C74H138N40O18
ANCEQHILMFSTWYV
R
1876.17
12.88
9
1
0
+8
9.63
-3.187
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
8
R
0
N
1
D
0
C
0
E
0
Q
3
G
0
H
0
I
0
L
1
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C74H138N40O18
1876.17
12.88
+8
9.63
-3.187
Free
Linker 6-aminohexamoic acid (Ahx)
L
Cationic
Linear
Conjugation with FITC
N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Fluorophore (FITC)
Membrane
Low (compare to Tat)
In vitro
CCCSSSCCTTTCCCC
Additional Detail Fields 1 fields
CCCSSSCCTTTCCCC