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Peptide record

TPDB63508

E3 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB63508
E3
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, Peptipedia, and PerseuCPP, with an available 3D structural model.
Sequence
RFTFHFRFEFTFHFE
Physicochemical Analysis
C105H131N25O22
ANDCQGILKMPSWYV
F
2095.35
8.00
4
2
7
+0
-0.05
-0.280
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
2
E
0
Q
0
G
2
H
0
I
0
L
0
K
0
M
7
F
0
P
0
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 2 Q: 0 G: 0 H: 2 I: 0 L: 0 K: 0 M: 0 F: 7 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C105H131N25O22
2095.35
8.00
+0
-0.05
-0.280
Free
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

C166-eGFP cells

Source & Reference

CPPsite3.0
CPPsite3
WO 2011/020188 A1

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCCCCCCCCSCCC
Additional Detail Fields 1 fields
CCCCCCCCCSCCC