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Peptide record

TPDB63493

P60 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB63493
P60
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RDFQSFRKMWPFFAM
Physicochemical Analysis
C95H132N24O20S2
NCEGHILTYV
F
1994.36
11.32
3
1
8
+2
-2.00
-0.427
6.67
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
275.78
2
Residue Composition
number
1
A
2
R
0
N
1
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
1
K
2
M
4
F
1
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 1 M: 2 F: 4 P: 1 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C95H132N24O20S2
1994.36
11.32
+2
-2.00
-0.427
Free
L
Linear
Free
N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Brca Cell Lines, Mouse Her2+ Breast Carcinoma Lm3 Cells, Eo771 Cells , MCF7 And Tnbc MDA-MB-231 And MDA-MB-468 Cell Lines

Assay & Model

Adult female BALB/c and C57Bl/6 (6–8 weeks old) mice
Adult female BALB/c and C57Bl/6 (6–8 weeks old) mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
adenoviral vector
In vitro and in vivo
CCCCC
Additional Detail Fields 1 fields
CCCCC