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Peptide record

TPDB63466

OTX2(HD)-TAMRA Cell-penetrating Peptides standard
60 amino acids
Basic Information
3D PDB MODEL
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TPDB63466
OTX2(HD)-TAMRA
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 60-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with TAMRA via Ahx linker
Sequence
QRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQ
Physicochemical Analysis
C325H529N103O89S2
GH
R
7367.53
11.26
14
7
23
+7
18.76
-0.878
73.17
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
6990
94.88
15
Residue Composition
number
5
A
10
R
2
N
2
D
1
C
5
E
6
Q
0
G
0
H
2
I
5
L
4
K
1
M
4
F
2
P
1
S
4
T
1
W
1
Y
4
V
Amino Acid Distribution
A: 5 R: 10 N: 2 D: 2 C: 1 E: 5 Q: 6 G: 0 H: 0 I: 2 L: 5 K: 4 M: 1 F: 4 P: 2 S: 1 T: 4 W: 1 Y: 1 V: 4
Chemical Descriptors
60
C325H529N103O89S2
7367.53
11.26
+7
18.76
-0.878
Free
L
Cationic
Linear
Conjugated with TAMRA via Ahx linker
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa And Dld-1 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic
Synthetic
TAMRA dye
Cytoplasm
In vitro