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Peptide record

TPDB63465

OTX2-HD Cell-penetrating Peptides standard
59 amino acids
Basic Information
3D PDB MODEL
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TPDB63465
OTX2-HD
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 59-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with FITC or TMR
Sequence
QRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCQQQ
Physicochemical Analysis
C319H517N99O88S2
GH
R
7211.34
10.92
13
7
23
+6
17.95
-0.817
74.41
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
6990
96.93
15
Residue Composition
number
5
A
9
R
2
N
2
D
1
C
5
E
6
Q
0
G
0
H
2
I
5
L
4
K
1
M
4
F
2
P
1
S
4
T
1
W
1
Y
4
V
Amino Acid Distribution
A: 5 R: 9 N: 2 D: 2 C: 1 E: 5 Q: 6 G: 0 H: 0 I: 2 L: 5 K: 4 M: 1 F: 4 P: 2 S: 1 T: 4 W: 1 Y: 1 V: 4
Chemical Descriptors
59
C319H517N99O88S2
7211.34
10.92
+6
17.95
-0.817
Free
Retro-inverso (L)
Linear
Conjugated with FITC or TMR
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa cells (wild type and KCNN4 KO)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear Retro-inverso (L)
FITC and TMR dye
Endocytosis
In vitro
CCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCC