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Peptide record

TPDB63455

pAntp (50-58) Cell-penetrating Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB63455
pAntp (50-58)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 9-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Biotinylation (Labeled with Biotinyl-beta-Alanine)
Sequence
QNRRMKWKK-NH2
Physicochemical Analysis
C55H95N21O12S1
ADCEGHILFPSTYV
K
1274.55
12.43
5
0
2
+5
3.51
-2.967
0.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
5500
431.52
2
Residue Composition
number
0
A
2
R
1
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
3
K
1
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 3 M: 1 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
9
C55H95N21O12S1
1274.55
12.43
+5
3.51
-2.967
Amidation
L
Linear
Biotinylation (Labeled with Biotinyl-beta-Alanine)
N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HaCat/ A549 cells

Source & Reference

CPPsite3.0
CPPsite3
US 7153931

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Biotin
Probably Cytosol and nucleus, nucleoi
Medium (60% relative to (pAntp) (43-58))
Non-endocytic mechanism
In vitro
CCCCSCCCC
Additional Detail Fields 1 fields
CCCCSCCCC