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Peptide record

TPDB63434

Cell-penetrating Peptides standard
44 amino acids
Basic Information
3D PDB MODEL
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TPDB63434
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 44-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: EBD_S11 fusion proteins
Sequence
PWAKRSLSSLQTSSRPVGRPSRQPRRGSSSKRRPRFRPTQAVSS
Physicochemical Analysis
C210H356N80O61
NDCEHIMY
S
4977.64
13.36
12
0
8
+12
11.95
-1.418
35.45
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
5500
110.49
16
Residue Composition
number
2
A
10
R
0
N
0
D
0
C
0
E
3
Q
2
G
0
H
0
I
2
L
2
K
0
M
1
F
6
P
11
S
2
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 10 N: 0 D: 0 C: 0 E: 0 Q: 3 G: 2 H: 0 I: 0 L: 2 K: 2 M: 0 F: 1 P: 6 S: 11 T: 2 W: 1 Y: 0 V: 2
Chemical Descriptors
44
C210H356N80O61
4977.64
13.36
+12
11.95
-1.418
Free
EBD_S11 fusion proteins
L
Linear
Free
N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hcc-827, Hek-293 , A431, CHO-K1 , Hl-60, Amo-1, T47D Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
GFP1–10 plasmid
Cytoplasm
Dose-dependent uptake
In vitro
CCSSSSSBCCSCTTCCCSSCCCBC
Additional Detail Fields 1 fields
CCSSSSSBCCSCTTCCCSSCCCBC