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Peptide record

TPDB63429

Cell-penetrating Peptides standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB63429
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 32-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: EBD_S11 fusion proteins
Sequence
PSSTPATNVARPRLNPIRGHKFALAVPNSRTR
Physicochemical Analysis
C151H253N53O42
DCEQMWY
RP
3483.00
13.00
7
0
10
+6
7.23
-0.703
67.19
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
9
Residue Composition
number
4
A
5
R
3
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
2
L
1
K
0
M
1
F
5
P
3
S
3
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 5 N: 3 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 2 K: 1 M: 0 F: 1 P: 5 S: 3 T: 3 W: 0 Y: 0 V: 2
Chemical Descriptors
32
C151H253N53O42
3483.00
13.00
+6
7.23
-0.703
Free
EBD_S11 fusion proteins
L
Linear
Free
N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hcc-827, Hek-293 , A431, CHO-K1 , Hl-60, Amo-1, T47D Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
GFP1–10 plasmid
Cytoplasm
Dose-dependent uptake
In vitro
CCCCSSSCCCCCCTTCCSSSSCCCTTCCCCCSCCSSSSCCSSCTTCC
Additional Detail Fields 1 fields
CCCCSSSCCCCCCTTCCSSSSCCCTTCCCCCSCCSSSSCCSSCTTCC