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Peptide record

TPDB63428

PreS2 3S Mutant Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB63428
PreS2 3S Mutant
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Conjugation with EGFP
Sequence
PSSSSSSRIGDP
Physicochemical Analysis
C46H77N15O21
ANCEQHLKMFTWYV
S
1176.21
6.78
1
1
1
-0
3.42
-0.992
32.50
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
6
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
1
I
0
L
0
K
0
M
0
F
2
P
6
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 2 S: 6 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C46H77N15O21
1176.21
6.78
-0
3.42
-0.992
Free
L
Non-amphipathic
Linear
Conjugation with EGFP
N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HepG2, HeLa and 293 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Non-amphipathic
Protein derived
Fluorophore (fluorescein)
Cytosol
Probably non-endocytic pathway
In vitro
CCCCCCCCCSCC
Additional Detail Fields 1 fields
CCCCCCCCCSCC