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Peptide record

TPDB63426

Protamine 3 (proticles 3) Cell-penetrating Peptides standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB63426
Protamine 3 (proticles 3)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 32-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
PRRRRSSSRPVRRRRRPRVSRRRRRRGGRRRR
Physicochemical Analysis
C167H319N95O37
ANDCEQHILKMFTWY
R
4249.98
13.70
21
0
2
+21
19.04
-2.966
18.12
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
4
Residue Composition
number
0
A
21
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
3
P
4
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 21 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 3 S: 4 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
32
C167H319N95O37
4249.98
13.70
+21
19.04
-2.966
Free
L
Cationic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

3T3-L1 Cell

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
miRNA-27a Nanoparticle
Cytoplasm
Concentration-dependent internalization
Endocytosis
In vitro
CCCSSSTTCCCTTTTC
Additional Detail Fields 1 fields
CCCSSSTTCCCTTTTC