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Peptide record

TPDB63414

(PPR)5 Blood-Brain Barrier Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB63414
(PPR)5
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
BBPpredict CPPsite3.0
standard
No
A 15-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from BBPpredict and CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with Cyanine5.5 (Cy5.5)
Sequence
PPRPPRPPRPPRPPR
Physicochemical Analysis
C80H132N30O16
ANDCEQGHILKMFSTWYV
P
1770.12
13.00
5
0
0
+5
8.55
-2.567
0.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
0
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
10
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 10 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C80H132N30O16
1770.12
13.00
+5
8.55
-2.567
Free
L
Amphipathic
Linear
Conjugated with Cyanine5.5 (Cy5.5)
N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Primary Human Astrocytes

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Cy5.5 dye
In vitro
CCBCTTSSBSSSSCCC
Additional Detail Fields 1 fields
CCBCTTSSBSSSSCCC