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Peptide record

TPDB63411

Secretory leukoprotease inhibitor derived PTD Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB63411
Secretory leukoprotease inhibitor derived PTD
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Conjugation with FITC
Sequence
PPKKSAQCLRYKKPE
Physicochemical Analysis
C79H133N23O21S1
NDGHIMFTWV
K
1773.13
10.31
5
1
3
+4
6.94
-1.727
32.67
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
1490
84.03
4
Residue Composition
number
1
A
1
R
0
N
0
D
1
C
1
E
1
Q
0
G
0
H
0
I
1
L
4
K
0
M
0
F
3
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 1 E: 1 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 4 M: 0 F: 0 P: 3 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
15
C79H133N23O21S1
1773.13
10.31
+4
6.94
-1.727
L
Linear
Conjugation with FITC
N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

P5 DRG neurons

Source & Reference

CPPsite3.0
CPPsite3
US20110107443

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (FITC)
Nucleus
Non-endocytic mechanism
In vitro
CCCGGGCCTTSCCCC
Additional Detail Fields 1 fields
CCCGGGCCTTSCCCC