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Peptide record

TPDB63410

1869_SpyT Cell-penetrating Peptides standard
64 amino acids
Basic Information
3D PDB MODEL
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TPDB63410
1869_SpyT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 64-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
PPHPRPLPAPAQSRKKQKGRAGRGHEKTGASVLRGPQKPHPLPAQLRGASAHIVMVDAYKPTKG
Physicochemical Analysis
C300H497N101O79S1
NCFW
P
6814.94
12.15
17
2
18
+11
22.02
-1.016
56.56
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
1490
21.86
10
Residue Composition
number
8
A
6
R
0
N
1
D
0
C
1
E
4
Q
7
G
4
H
1
I
4
L
7
K
1
M
0
F
11
P
3
S
2
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 8 R: 6 N: 0 D: 1 C: 0 E: 1 Q: 4 G: 7 H: 4 I: 1 L: 4 K: 7 M: 1 F: 0 P: 11 S: 3 T: 2 W: 0 Y: 1 V: 3
Chemical Descriptors
64
C300H497N101O79S1
6814.94
12.15
+11
22.02
-1.016
Free
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO-K1 Or T47D Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
β-lactamase protein and CCF2-AM cell-permeable dye
Cytoplasm
In vitro
CCTTHHHHHHHTTCSGGGCSCCCSCHHHIIIIITSSCCCSCSCCCSCC
Additional Detail Fields 1 fields
CCTTHHHHHHHTTCSGGGCSCCCSCHHHIIIIITSSCCCSCSCCCSCC