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Peptide record

TPDB63397

0169_SpyT Cell-penetrating Peptides standard
60 amino acids
Basic Information
3D PDB MODEL
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TPDB63397
0169_SpyT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 60-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
PLTQRTLQRGKKPKQRQNWKKARTSSAKTAPKTVVSRTTSQRKGASAHIVMVDAYKPTKG
Physicochemical Analysis
C289H497N97O83S1
CEF
K
6690.79
12.44
17
1
16
+15
18.68
-1.192
48.83
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
6990
104.47
20
Residue Composition
number
6
A
6
R
1
N
1
D
0
C
0
E
5
Q
3
G
1
H
1
I
2
L
10
K
1
M
0
F
4
P
5
S
8
T
1
W
1
Y
4
V
Amino Acid Distribution
A: 6 R: 6 N: 1 D: 1 C: 0 E: 0 Q: 5 G: 3 H: 1 I: 1 L: 2 K: 10 M: 1 F: 0 P: 4 S: 5 T: 8 W: 1 Y: 1 V: 4
Chemical Descriptors
60
C289H497N97O83S1
6690.79
12.44
+15
18.68
-1.192
Free
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO-K1 Or T47D Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
β-lactamase protein and CCF2-AM cell-permeable dye
Cytoplasm
In vitro
CCCCCCCGGGCCCCCSSSCCCCCCEETTEECCCCCCTTCCCCC
Additional Detail Fields 1 fields
CCCCCCCGGGCCCCCSSSCCCCCCEETTEECCCCCCTTCCCCC