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Peptide record

TPDB63395

CPP TLM-anti-gyrA PNA/scPNA Blood-Brain Barrier Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB63395
CPP TLM-anti-gyrA PNA/scPNA
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
BBPpredict CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from BBPpredict, CellPPD, CPPsite3.0, and other sources, with an available 3D structural model.
Sequence
PLSSIFSRIGDP
Physicochemical Analysis
C58H93N15O18
ANCEQHKMTWYV
S
1288.47
6.78
1
1
4
-0
1.03
0.133
97.50
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
3
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
2
I
1
L
0
K
0
M
1
F
2
P
3
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 1 K: 0 M: 0 F: 1 P: 2 S: 3 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C58H93N15O18
1288.47
6.78
-0
1.03
0.133
Free
L
Linear
Free
N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)O N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

S. Pyogenes Strains

Assay & Model

G. mellonella Larvae
G. mellonella Larvae

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
anti-gyrA antisense PNAs and scrambled PNAs [scPNAs]
In vitro and in vivo
CCCSCC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

Hct 116 And MDA-MB-453 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L
RIP saporin ,dianthin and EGF
Cytosol
In vitro
CCCSSSCCCC
Additional Detail Fields 1 fields
CCCSCC CCCSSSCCCC