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Peptide record

TPDB63393

1746_SpyT Cell-penetrating Peptides standard
55 amino acids
Basic Information
3D PDB MODEL
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TPDB63393
1746_SpyT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 55-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
PLKPKKPKTQEKKKKQPPKPKKPKTQEKKKKQPPKPKRGASAHIVMVDAYKPTKG
Physicochemical Analysis
C285H494N84O71S1
NCFW
K
6265.64
11.11
22
3
9
+18
32.27
-1.978
30.18
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
1490
23.78
9
Residue Composition
number
3
A
1
R
0
N
1
D
0
C
2
E
4
Q
2
G
1
H
1
I
1
L
20
K
1
M
0
F
11
P
1
S
3
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 1 C: 0 E: 2 Q: 4 G: 2 H: 1 I: 1 L: 1 K: 20 M: 1 F: 0 P: 11 S: 1 T: 3 W: 0 Y: 1 V: 2
Chemical Descriptors
55
C285H494N84O71S1
6265.64
11.11
+18
32.27
-1.978
Free
L
Linear
Free
NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO-K1 Or T47D Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
β-lactamase protein and CCF2-AM cell-permeable dye
Cytoplasm
In vitro
CCCCCCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCCCCCC