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Peptide record

TPDB63385

NLS-pep8 Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB63385
NLS-pep8
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 27-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Acetylation
Sequence
Ac-PKKKRRVEASALVCIRLVTSSKPRTVA
Physicochemical Analysis
C130H237N43O35S1
NDQGHMFWY
RKV
2994.64
11.99
8
1
10
+7
8.89
-0.270
97.41
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
6
Residue Composition
number
3
A
4
R
0
N
0
D
1
C
1
E
0
Q
0
G
0
H
1
I
2
L
4
K
0
M
0
F
2
P
3
S
2
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 3 R: 4 N: 0 D: 0 C: 1 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 4 M: 0 F: 0 P: 2 S: 3 T: 2 W: 0 Y: 0 V: 4
Chemical Descriptors
27
C130H237N43O35S1
2994.64
11.99
+7
8.89
-0.270
Free
L
Linear
Acetylation
N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

4T1, B16-F0, A549, MDA-MB-23, Hepg2 And Panc-1 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
In vitro
CCCCCSCSSSCCCCTTSTTCSTTTSCC
Additional Detail Fields 1 fields
CCCCCSCSSSCCCCTTSTTCSTTTSCC