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Peptide record

TPDB63383

Cell-penetrating Peptides standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB63383
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 32-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
Sequence
PKKKRKVRRRRRRRYSQTSHKLVQLLTTAEQQ
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C172H307N67O45
NDCGIMFW
R
4033.75
12.63
14
1
7
+12
5.34
-1.913
57.81
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
1490
0.37
10
Residue Composition
number
1
A
8
R
0
N
0
D
0
C
1
E
4
Q
0
G
1
H
0
I
3
L
5
K
0
M
0
F
1
P
2
S
3
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 8 N: 0 D: 0 C: 0 E: 1 Q: 4 G: 0 H: 1 I: 0 L: 3 K: 5 M: 0 F: 0 P: 1 S: 2 T: 3 W: 0 Y: 1 V: 2
Chemical Descriptors
32 reviewed residue count
C172H307N67O45 sequence-only estimate (linear, free termini)
4033.75 sequence-only estimate (linear, free termini)
12.63 sequence-only estimate (linear, free termini)
+12 sequence-only estimate (linear, free termini)
5.34 sequence-only estimate (linear, free termini)
-1.913 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.