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Peptide record

TPDB63382

Cell-penetrating Peptides standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB63382
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 37-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, and Peptipedia, with an available 3D structural model.
Sequence
PKKKRKVRRRRRRRPQMQQNVFQYPGAGMVPQGEANF
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C194H324N72O48S2
DCHILSTW
R
4497.28
12.63
12
1
10
+11
4.33
-1.700
28.92
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
1490
0.33
8
Residue Composition
number
2
A
8
R
2
N
0
D
0
C
1
E
5
Q
3
G
0
H
0
I
0
L
4
K
2
M
2
F
4
P
0
S
0
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 2 R: 8 N: 2 D: 0 C: 0 E: 1 Q: 5 G: 3 H: 0 I: 0 L: 0 K: 4 M: 2 F: 2 P: 4 S: 0 T: 0 W: 0 Y: 1 V: 3
Chemical Descriptors
37 reviewed residue count
C194H324N72O48S2 sequence-only estimate (linear, free termini)
4497.28 sequence-only estimate (linear, free termini)
12.63 sequence-only estimate (linear, free termini)
+11 sequence-only estimate (linear, free termini)
4.33 sequence-only estimate (linear, free termini)
-1.700 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.