Back to search

Peptide record

TPDB63377

FITC-HNLS-1 Cell-penetrating Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63377
FITC-HNLS-1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 9-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
PKKKRKVGK-NH2
Physicochemical Analysis
C48H93N17O10
ANDCEQHILMFSTWY
K
1068.37
11.85
6
0
1
+6
6.29
-2.422
32.22
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
5
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 5 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
9
C48H93N17O10
1068.37
11.85
+6
6.29
-2.422
Amidation
L
Linear
Free
N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC1=NC=NC1)C(=O)NCC(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cell Line

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
FITC-conjugated at C terminus
CPP activity of FITC-HNLS-1 did not notably change.
In vitro
CCSSCCSCCCTTSCC
Additional Detail Fields 1 fields
CCSSCCSCCCTTSCC