Back to search

Peptide record

TPDB63354

PS-unacet.-STAT3 peptide Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63354
PS-unacet.-STAT3 peptide
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: Phosphorothioated (PS) polymer
Sequence
PDIPKEEAFGKYCRPESQEHPC
Physicochemical Analysis
C111H166N30O36S2
NLMTWV
EP
2560.84
4.76
4
5
4
-2
12.55
-1.423
22.27
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
1615
63.07
5
Residue Composition
number
1
A
1
R
0
N
1
D
2
C
4
E
1
Q
1
G
1
H
1
I
0
L
2
K
0
M
1
F
4
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 1 C: 2 E: 4 Q: 1 G: 1 H: 1 I: 1 L: 0 K: 2 M: 0 F: 1 P: 4 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
22
C111H166N30O36S2
2560.84
4.76
-2
12.55
-1.423
Free
Phosphorothioated (PS) polymer
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Murine B16 Melanoma, Human Hct116 Colon Carcinoma, Human Lovo Metastatic Crc, U251 Human Glioma Cell, Kpc Mouse Cell

Assay & Model

NSG mice bearing HCT116 tumor cells
NSG mice bearing HCT116 tumor cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
FAM dye and Oligonucleotide
Probably Cytoplasm
In vitro and in vivo
CCCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCCC