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Peptide record

TPDB63353

PDESTK-anti-gyrA PNA/scPNA Cell-penetrating Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB63353
PDESTK-anti-gyrA PNA/scPNA
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 6-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
PDESTK
Physicochemical Analysis
C27H45N7O13
ARNCQGHILMFWYV
DEKPST
675.69
4.07
1
2
0
-1
4.96
-2.333
0.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
2
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
1
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
1
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C27H45N7O13
675.69
4.07
-1
4.96
-2.333
Free
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

S. Pyogenes Strains

Assay & Model

G. mellonella Larvae
G. mellonella Larvae

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
anti-gyrA antisense PNAs and scrambled PNAs [scPNAs]
No antimicrobial activity of PDSTK-conjugated antisense PNA in S. pyogenes.
In vitro and in vivo
CCSTTCCC
Additional Detail Fields 1 fields
CCSTTCCC