Back to search

Peptide record

TPDB63352

CASC3(251-264) Cell-penetrating Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63352
CASC3(251-264)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 14-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugated with 6-Carboxyfluorescein (6-Fam)
Sequence
PDDIKPRRIRKPRY-NH2
Physicochemical Analysis
C80H136N28O20
ANCEQGHLMFSTWV
R
1810.14
11.34
6
2
3
+4
7.47
-2.136
55.71
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
1490
82.31
1
Residue Composition
number
0
A
4
R
0
N
2
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
2
K
0
M
0
F
3
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 2 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 2 M: 0 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
14
C80H136N28O20
1810.14
11.34
+4
7.47
-2.136
Amidation
L
Linear
Conjugated with 6-Carboxyfluorescein (6-Fam)
N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U87, PC3, And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
FAM-conjugated
Highest fluorescence intensities by 1-2-fold
In vitro
CCCCSTTTTC
Additional Detail Fields 1 fields
CCCCSTTTTC